Peracetic Acid → HCID 23341978, compound

HRID 27746Notes

Reaction equation

HRID 27746 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:10][C:9]3=[CH:11][NH:12][C:13](=[O:17])[C:14]([C:15]#[N:16])=[C:8]3[NH:7][C:6]=2[CH:18]=1.C(OO)(=[O:21])C>C(O)(=O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:10](=[O:21])[C:9]3=[CH:11][NH:12][C:13](=[O:17])[C:14]([C:15]#[N:16])=[C:8]3[NH:7][C:6]=2[CH:18]=1

Participants

4

Reactant 2

HCID 6585Peracetic AcidHCID 233420167-chloro-2,3-dihydro-3-oxo-5H-pyrido[3,4-b][1,4]benzothiazine-4-carbonitrile

Product 1

HCID 23341978HCID 23341978, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 1 part of 7-chloro-2,3-dihydro-3-oxo-5H-pyrido[3,4-b][1,4]benzothiazine-4-carbonitrile, 14 parts of ethaneperoxoic acid, and 58 parts of acetic acid is stirred at room temperature for 27 hours, whereupon insoluble solids are filtered out, dried in air, and recrystallized from aqueous N,N-dimethylformamide to give 7-chloro-2,3-dihydro-3-oxo-5H-pyrido[3,4-b][1,4]benzothiazine-4-carbonitrile 10-oxide as a colorless solid melting above 300°.

Workup

  1. filtrationare filtered out
  2. customdried in air
  3. customrecrystallized from aqueous N,N-dimethylformamide

Sources & evidence

ORD record
ord-deeee688c52f42f1819134235fbc2faa
Source dataset
uspto-grants-1980_09
Patent number
US04223136

Reaction notes

Loading…