HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → Methyl 3-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 15654690 | HCID 15654690 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 3-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate | HCID 15654691 | — |
Reaction Steps
To a solution of methyl 2-[(2′-cyanobiphenyl-4-yl)methylamino]-3-methoxycarbonylaminobenzoate (10.5 g) in methanol (100 ml) was added NaOMe (10 g), and the mixture was heated under reflux for 20 hours. The reaction mixture was neutralized with
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06355808B2 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-abc52caf150c4381b19b658bf8a0dbf6 |
| Source note | uspto-grants-2002_03 |