HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-[(7,8-dihydro-8,8-dimethylnaphth-3-yl)ethynyl]benzoate → 4-[(7,8-Dihydro-8,8-dimethylnaphth-3-yl)ethynyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-[(7,8-dihydro-8,8-dimethylnaphth-3-yl)ethynyl]benzoate | HCID 18314571 | — |
| Reactant | 4-[(7,8-Dihydro-8,8-dimethyl-5-(1,1-dimethylethyl)naphth-3-yl)ethynyl]benzoic acid | HCID 18314596 | — |
| Product | 4-[(7,8-Dihydro-8,8-dimethylnaphth-3-yl)ethynyl]benzoic acid | HCID 18314580 | — |
Reaction Steps
Employing the same general procedure as for the preparation of 4-[(7,8-dihydro-8,8-dimethyl-5-(1,1-dimethylethyl)naphth-3-yl)ethynyl]benzoic acid (Compound 80), 25.3 mg (0.08 mmol) of ethyl 4-[(7,8-dihydro-8,8-dimethylnaphth-3-yl)ethynyl]benzoate (Compound 72) was converted into the title compound (colorless solid) using 8.0 mg (0.14 mmol) of LiOH in H2O.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06355806B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-7a2ec5e9602e429aa11c41349e1f9ce7 |
| Source note | uspto-grants-2002_03 |