Selenium Dioxide → 5-Cyano-6-formyl-2-[[3-(trifluormethyl)phenyl]amino]-3-pyridine-carboxylic acid, ethyl ester

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69.8 g of 5-cyano-6-methyl-2-[[3-(trifluormethyl)phenyl]amino]-3-pyridine-carboxylic acid, ethyl ester (0.2 mol) are dissolved in 400 ml of diethyleneglycoldimethyl ether. After addition of 24.2 g of selenium dioxide, the mixture is heated at 160° with stirring for 2 hrs. The selenium is filtered off and the filtrate evaporated. The resulting yellow title compound is recrystallized from butanol. Yield 56 g (77%); m.p. 183°-185° C.

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