HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 22625376, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | ((p-(Benzyloxy)phenoxy)methyl)oxirane | HCID 119882 | — |
| Reactant | 1-(2,5-Dimethoxyphenyl)piperazine dihydrochloride | HCID 13599003 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 22625376 | HCID 22625376 | 33.9% |
Reaction Steps
2.56 g of 1-(4-benzyloxyphenoxy)-2,3-epoxypropane was dissolved in 100 ml of dioxane, and to this were added 2.95 g of 1-(2,5-dimethoxyphenyl)piperazine dihydrochloride and 3.5 ml of triethylamine and reaction and workup were carried out as in Example 1-A. The residue obtained was purified by column chromatography (silica gel, elution with ethyl acetate:hexane=1:1) to give 1.62 g of brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358515B2 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-74ab6cf6ea5342a989d4f284f57cbbbb |
| Source note | uspto-grants-2002_03 |