HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 2-Methylbenzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | O-Phenylenediamine | HCID 7243 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Product | 2-Methylbenzimidazole | HCID 11984 | 77% |
Reaction Steps
Phenylene diamine (32 grams) and glacial acetic acid (60 ml) were refluxed for 2 hours. Ice and KOH were added to bring the pH to 8.0, and the resulting light violet solid was filtered and collected. Recrystallization from benzene yielded 30 grams of 2-methyl benzimidazole as a light yellow solid having a melting point of 170° C. and total yield of 77%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358954B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-f662b28ea364484e9f360e8e760b0282 |
| Source note | uspto-grants-2002_03 |