HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4'-Cyanobenzyl)imidazol-5-ylmethyl Piperazine-4-carboxylic Acid Benzyl Ester → 1-(4'-Cyanobenzyl)imidazol-5-ylmethyl piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4'-Cyanobenzyl)imidazol-5-ylmethyl Piperazine-4-carboxylic Acid Benzyl Ester | HCID 86585292 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(4'-Cyanobenzyl)imidazol-5-ylmethyl piperazine | HCID 53655335 | — |
Reaction Steps
The product from Step 1 (6.17 mmol) was dissolved in absolute ethanol followed by the introduction of 10% Pd/C catalyst then hydrogen under atmospheric pressure. The catalyst was removed via filtration through filter-aid and the product was isolated by removing the solvent under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358956B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-9fe3bfb49edc452dbd17bffb46158979 |
| Source note | uspto-grants-2002_03 |