HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromothiophene-2-carbonitrile → HCID 10424022, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromothiophene-2-carbonitrile | HCID 14292355 | — |
| Reactant | 6-Bromo-2,4,4-trimethyl-2,4-dihydro-1H-benzo[D][1,3]oxazine | HCID 23435574 | — |
| Product | HCID 10424022 | HCID 10424022 | — |
Reaction Steps
Prepared according to the procedure for Example 13 from 6-bromo-2,4,4-trimethyl-1,4-dihydro-2H-3,1-benzoxazine and 4-bromo-2-thiophenecarbonitrile. An off-white solid: mp 175-176° C.; 1H-NMR (DMSO-d6) δ 8.39 (d, 1H, J=1.5 Hz), 8.13 (d, 1H, J=1.5 Hz), 7.47 (d, 1H, J=1.9 Hz), 7.36 (dd, 1H, J=8.4, 1.9 Hz), 6.59 (d, 1H, J=8.4 Hz), 6.41 (s, 1H), 4.78 (m, 1H), 1.51 (s, 3H), 1.47 (s, 3H), 1.28 (d, 3H, J=5.4 Hz); MS (ESI) m/z 285 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358948B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-0c266987a47042d38966eb7d7ed7bc5d |
| Source note | uspto-grants-2002_03 |