HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromothiophene-2-carbonitrile → 4-(2-Methylspiro[2H-3,1-benzoxazine-4,1'-cyclopentane]-6-yl)-2-thiophenecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromothiophene-2-carbonitrile | HCID 14292355 | — |
| Reactant | 2-methyl-6-bromospiro[4H-3,1-benzoxazine-4,1'-cyclopentane] | HCID 23435585 | — |
| Product | 4-(2-Methylspiro[2H-3,1-benzoxazine-4,1'-cyclopentane]-6-yl)-2-thiophenecarbonitrile | HCID 23435612 | — |
Reaction Steps
Prepared according to the procedure for Example 13 from 2-methyl-6-bromospiro[4H-3,1-benzoxazine-4,1′-cyclopentane] and 4-bromo-2-thiophenecarbonitrile. An off-white solid: mp 103-104° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358948B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-dce983b6390242998be08c3c51969038 |
| Source note | uspto-grants-2002_03 |