HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 22626819, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | (3-Methoxyphenyl)acetonitrile | HCID 88310 | — |
| Reactant | Cyclopentylmethyl 4-methylbenzene-1-sulfonate | HCID 12568544 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22626819 | HCID 22626819 | 50.1% |
Reaction Steps
By working in a way similar to that described in example 2 but using toluen-4-sulphonic acid cyclopentylmethyl ester (5.09 g, 20 mmoles), obtained as described in example 6, 3-methoxy-phenyl-acetonitrile (2.94 g, 20 mmoles), NaH (55-65%, 880 mg, 22 mmoles) and DMF (25 ml), 2.3 g of the title compound were obtained (yield: 50.1%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358973B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-b7d935066d1d4426a091d19f4adf324d |
| Source note | uspto-grants-2002_03 |