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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 277906Generated: October 29, 2026

Aluminium lithium hydride → 2-(3-Methoxy-phenyl)-4-methyl-pentylamine

https://huagongshe.com/reaction/277906

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAluminium lithium hydrideHCID 21226445—
ReactantHCID 22626833HCID 22626833—
SolventDiethyl EtherHCID 3283—
Product2-(3-Methoxy-phenyl)-4-methyl-pentylamineHCID 2262684493.8%

Reaction Steps

By working in a way similar to that described in example 17 but using LiAlH4 (0.7 g, 0.018 moles) in anhydrous ethyl ether (35 ml) and 2-(3-methoxy-phenyl)-4-methyl-pentan-nitrile (3.8 g, 0.018 moles), obtained as described in example 20, in anhydrous ethyl ether (35 ml), 3.5 g of the title compound were obtained (yield: 90.4%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06358973B1
Source datasetuspto-grants-2002_03
ORD IDord-151e1751a9144f2e8d81db96c30b2620
Source noteuspto-grants-2002_03