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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 277907Generated: October 30, 2026

1,1'-Carbonyldiimidazole → HCID 22626834, compound

https://huagongshe.com/reaction/277907

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantHCID 22626827HCID 22626827—
Reactant2-(3-Methoxy-phenyl)-4-methyl-pentylamineHCID 22626844—
SolventTetrahydrofuranHCID 8028—
ProductHCID 22626834HCID 2262683497.6%

Reaction Steps

By working in a way similar to that described in example 4 but using (3,5-dichloropyridin-4-yl)-acetic acid (2.06 g, 10 mmoles), carbonyldiimidazole (1.78 g, 11 mmoles), THF (30 ml) and 2-(3-methoxy-phenyl)-4-methyl-pentylamine (2.07 g, 10 mmoles), obtained as described in example 21, 3.85 g of the title compound were obtained (yield: 97.6%), m.p.: 98-99° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06358973B1
Source datasetuspto-grants-2002_03
ORD IDord-8f0852674e6949dba88b72a63e558070
Source noteuspto-grants-2002_03