HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Bromide → HCID 12665498, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Bromide | HCID 6332 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | (3-Methoxyphenyl)acetonitrile | HCID 88310 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 12665498 | HCID 12665498 | 58% |
Reaction Steps
By working in a way similar to that described in example 16 but using 3-methoxy-phenyl-acetonitrile (8.8 g, 60 mmoles), DMF (60 ml), NaH (60%, 2.88 g, 72 mmoles) and ethylbromide (7.85 g, 72 mmoles), and chromatographing with petrolatum/ethyl ether 97:3 as eluent, 6.1 g of the title compound were obtained (yield: 58%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358973B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-758f8c22277748a2b95a0a1d1125bf27 |
| Source note | uspto-grants-2002_03 |