HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Carbonyldiimidazole → HCID 22626845, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 2-(3-Methoxyphenyl)butan-1-amine | HCID 14528073 | — |
| Reactant | HCID 22626827 | HCID 22626827 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22626845 | HCID 22626845 | 96.7% |
Reaction Steps
By working in a way similar to that described in example 4 but using (3,5-dichloro-pyridin-4-yl)-acetic acid (2.06 g, 10 mmoles), carbonyldiimidazole (1.78 g, 11 mmoles), THF (30 ml) and 2-(3-methoxy-phenyl)-butylamine (1.79 g, 10 mmoles), obtained as described in example 25, 3.55 g of the title compound were obtained (yield: 96.7%). m.p.: 104-105° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358973B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-6267f54977c54fd0a40b1718a1b50b55 |
| Source note | uspto-grants-2002_03 |