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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 277909Generated: October 30, 2026

1,1'-Carbonyldiimidazole → HCID 22626845, compound

https://huagongshe.com/reaction/277909

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant2-(3-Methoxyphenyl)butan-1-amineHCID 14528073—
ReactantHCID 22626827HCID 22626827—
SolventTetrahydrofuranHCID 8028—
ProductHCID 22626845HCID 2262684596.7%

Reaction Steps

By working in a way similar to that described in example 4 but using (3,5-dichloro-pyridin-4-yl)-acetic acid (2.06 g, 10 mmoles), carbonyldiimidazole (1.78 g, 11 mmoles), THF (30 ml) and 2-(3-methoxy-phenyl)-butylamine (1.79 g, 10 mmoles), obtained as described in example 25, 3.55 g of the title compound were obtained (yield: 96.7%). m.p.: 104-105° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06358973B1
Source datasetuspto-grants-2002_03
ORD IDord-6267f54977c54fd0a40b1718a1b50b55
Source noteuspto-grants-2002_03