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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278065Generated: October 30, 2026

HCID 53794293, compound → Methyl 2-propylindole-6-carboxylate

https://huagongshe.com/reaction/278065

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 53794293HCID 53794293—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
SolventEthyl AcetateHCID 8857—
ProductMethyl 2-propylindole-6-carboxylateHCID 2262729590.6%

Reaction Steps

To a solution of methyl 1-benzyloxycarbonyl-2-propylindole-6-carboxylate (200 mg) in a mixture of methanol and ethyl acetate (1:1, 8 ml) was added 10% palladium on carbon (30 mg), and the mixture was stirred under hydrogen atmosphere or 20 minutes. The catalyst was removed by filtration through celite and washed with methanol. The filtrate was evaporated in vacuo to give methyl 2-propylindole-6-carboxylate (112 mg) as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06358992B1
Source datasetuspto-grants-2002_03
ORD IDord-beafc8a0ee6f40ed892c4de4a93a8b3a
Source noteuspto-grants-2002_03