HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 53794293, compound → Methyl 2-propylindole-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 53794293 | HCID 53794293 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Methyl 2-propylindole-6-carboxylate | HCID 22627295 | 90.6% |
Reaction Steps
To a solution of methyl 1-benzyloxycarbonyl-2-propylindole-6-carboxylate (200 mg) in a mixture of methanol and ethyl acetate (1:1, 8 ml) was added 10% palladium on carbon (30 mg), and the mixture was stirred under hydrogen atmosphere or 20 minutes. The catalyst was removed by filtration through celite and washed with methanol. The filtrate was evaporated in vacuo to give methyl 2-propylindole-6-carboxylate (112 mg) as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358992B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-beafc8a0ee6f40ed892c4de4a93a8b3a |
| Source note | uspto-grants-2002_03 |