反应详情

A solution of methyl 4-(1-dimethylaminomethylene-2-oxopentyl)-3-nitrobenzoate (172 mg) in dioxane (9 ml) was refluxed For 4 days. The resulting mixture was evaporated in vacuo, and the residue was purified by thin layer chromatography with a mixture of hexane and ethyl acetate (2:1) to give methyl 3-nitro-4-(2-oxopentyl)benzoate (127 mg).

1. customThe resulting mixture was evaporated in vacuo
2. customthe residue was purified by thin layer chromatography with a mixture of hexane and ethyl acetate (2:1)