HRID27811

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID887

Methanol

CH4O

HCID6212

Chloroform

CHCl3

结构：COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccccc1)C(C)C

HCID131711891

未命名化合物

PRODUCTS

生成物

结构：COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C.Cl

HCID131711889

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID176

Acetic Acid

C2H4O2

PROCEDURE

实验过程

Compound (iii) (6.87 g) was BOC-deprotected in 2 N HCl in EtAc (100 ml) for 2 hours at room temperature when a white solid precipitated (5.84 g) representing 97% yield of product. M.P. 243°-245° (decomposition). T.L.C. in 9:1 CHCl3 :MeOH (I2 stain) shows one spot at Rf 0.59. [α]D25 =8.8° (C=1, AcOH). (v) BOC.PhePheValPheOMe