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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278148Generated: October 30, 2026

4-Fluorobenzaldehyde → E-4-fluorostyryl 4-chlorobenzyl sulfone

https://huagongshe.com/reaction/278148

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzaldehydeHCID 68023—
Reactant[(4-Chlorobenzyl)sulfonyl]acetic acidHCID 302767—
ProductE-4-fluorostyryl 4-chlorobenzyl sulfoneHCID 986152372%

Reaction Steps

A solution of 4-chlorobenzyl sulfonylacetic acid (0.01 mol) and 4-fluorobenzaldehyde (0.01 mol) was subjected to Procedure 1. The title compound was obtained in 72% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06359013B1
Source datasetuspto-grants-2002_03
ORD IDord-108c67e68abd4e1fa68377aec049235f
Source noteuspto-grants-2002_03