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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278151Generated: October 30, 2026

2,4-Difluorobenzaldehyde → E-2,4-difluorostyryl 4-fluorobenzyl sulfone

https://huagongshe.com/reaction/278151

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzaldehydeHCID 73770—
Reactant[(4-Fluorobenzyl)sulfonyl]acetic acidHCID 11447598—
ProductE-2,4-difluorostyryl 4-fluorobenzyl sulfoneHCID 988323268%

Reaction Steps

A solution of 4-fluorobenzyl sulfonylacetic acid (0.01 mol) and 2.4-difluorobenzaldehyde (0.01 mol) was subjected to Procedure 1. The title compound was obtained in 68% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06359013B1
Source datasetuspto-grants-2002_03
ORD IDord-4fabeb2f0a614f8ebafeaab95a2e2d7e
Source noteuspto-grants-2002_03