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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278163Generated: November 4, 2026

1-Azido-3-(3-methoxyphenyl)-1-phenylpropane → 3-(3-Methoxyphenyl)-1-phenylpropylamine

https://huagongshe.com/reaction/278163

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Azido-3-(3-methoxyphenyl)-1-phenylpropaneHCID 22627107—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product3-(3-Methoxyphenyl)-1-phenylpropylamineHCID 22627103—

Reaction Steps

A solution of the product from Step B (1.08 g, 3.7 mmol) in 30 mL of EtOH containing Pd/C (10%, 100 mg) was stirred at ambient temperature under 1 Atm. of H2 for 20 hours. The reaction mixture was filtered to provide the title product as a clear colorless oil which was sufficiently pure for use in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06358985B1
Source datasetuspto-grants-2002_03
ORD IDord-9d0a4ee5be92430b8bf18e32271c5dab
Source noteuspto-grants-2002_03