HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 18187862, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 18187735 | HCID 18187735 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 18187862 | HCID 18187862 | — |
Reaction Steps
A solution of 1-(t-butoxycarbonyl)-4-(3-(quinolin-3-yl)propyl)piperidine from Step A (240 mg, 0.68 mmol) in 1M HCl solution (8 mL) in methanol was stirred at rt for 48 h. The solution was concentrated and the residue crystallized from ethyl acetate to afford the title compound (182 mg),
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358979B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-c69722b8a727498aba062bc813a1d126 |
| Source note | uspto-grants-2002_03 |