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HRID278243

反应详情

EQUATION

反应方程式

HRID 278243 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)c1ccnc(N)c1
HCID12351941

未命名化合物

结构：CC(C)(C)OC(=O)N1CCC(C(Br)C=O)CC1
HCID21912701

tert-Butyl 4-(1-bromo-2-oxoethyl)piperidine-1-carboxylate

C12H20BrNO3

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC(c2cnc3cc(C(C)(C)C)ccn23)CC1
HCID21912757

1,1-Dimethylethyl 4-[7-(1,1-dimethylethyl)imidazo[1,2-a]pyridin-3-yl]-1-piperidinecarboxylate

C21H31N3O2

收率 23.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

The title compound was prepared from 470 mg of 1-(t-butoxycarbonyl)-4-(1-bromo-2-oxoethyl)piperidine (from Procedure 23, Step C) and 277 mg of 2-amino-4-t-butyl pyridine (from Step A) in 12 mL ethanol using a procedure analogous to that described in Example 235, Step A to provide 130 mg of the title compound as a solid.