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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278424Generated: November 2, 2026

(RS)-5-Benzyloxy-2-bromomethyl-2,3-dihydro-benzofuran → (RS)-4-(3,4-Dimethyl-benzyl)-1-(5-benzyloxy-2,3-dihydro-benzofuran-2-ylmethyl)-piperidin-4-ol

https://huagongshe.com/reaction/278424

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(RS)-5-Benzyloxy-2-bromomethyl-2,3-dihydro-benzofuranHCID 22628347—
Reactant4-(3,4-Dimethyl-benzyl)-piperidin-4-olHCID 22628397—
Product(RS)-4-(3,4-Dimethyl-benzyl)-1-(5-benzyloxy-2,3-dihydro-benzofuran-2-ylmethyl)-piperidin-4-olHCID 22628380—

Reaction Steps

The title compound MS: m/e=458.6 (M+H+) was prepared from 4-(3,4-dimethyl-benzyl)-piperidin-4-ol and 5-benzyloxy-2-(RS)-bromomethyl-2,3-dihydro-benzofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06359138B1
Source datasetuspto-grants-2002_03
ORD IDord-3a915db050874a32b3d564c47f649739
Source noteuspto-grants-2002_03