(RS)-5-Benzyloxy-2-bromomethyl-2,3-dihydro-benzofuran → HCID 22628387, compound

HRID 278426Notes

Reaction equation

HRID 278426 reaction equation
[CH:1]([C:4]1[CH:17]=[CH:16][C:7]([CH2:8][C:9]2([OH:15])[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]2)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[CH2:18]([O:25][C:26]1[CH:27]=[CH:28][C:29]2[O:33][CH:32]([CH2:34]Br)[CH2:31][C:30]=2[CH:36]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH:1]([C:4]1[CH:17]=[CH:16][C:7]([CH2:8][C:9]2([OH:15])[CH2:10][CH2:11][N:12]([CH2:34][CH:32]3[CH2:31][C:30]4[CH:36]=[C:26]([O:25][CH2:18][C:19]5[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=5)[CH:27]=[CH:28][C:29]=4[O:33]3)[CH2:13][CH2:14]2)=[CH:6][CH:5]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 22628347(RS)-5-Benzyloxy-2-bromomethyl-2,3-dihydro-benzofuranHCID 22628378HCID 22628378, compound

Product 1

HCID 22628387HCID 22628387, compound

Procedure

The title compound MS: m/e=472.6 (M+H+) was prepared from 4-(4-isopropyl-benzyl)-piperidin-4-ol and 5-benzyloxy-2-(RS)-bromomethyl-2,3-dihydro-benzofuran.

Sources & evidence

ORD record
ord-45795bd01e0a4349a06286d7686a04eb
Source dataset
uspto-grants-2002_03
Patent number
US06359138B1

Reaction notes

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