(RS)-5-Benzyloxy-2-bromomethyl-2,3-dihydro-benzofuran → HCID 22628370, compound

HRID 278427Notes

Reaction equation

HRID 278427 reaction equation
[CH3:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[CH2:4][C:5]1([OH:11])[CH2:10][CH2:9][NH:8][CH2:7][CH2:6]1.[CH2:16]([O:23][C:24]1[CH:25]=[CH:26][C:27]2[O:31][CH:30]([CH2:32]Br)[CH2:29][C:28]=2[CH:34]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH3:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[CH2:4][C:5]1([OH:11])[CH2:6][CH2:7][N:8]([CH2:32][CH:30]2[CH2:29][C:28]3[CH:34]=[C:24]([O:23][CH2:16][C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=4)[CH:25]=[CH:26][C:27]=3[O:31]2)[CH2:9][CH2:10]1

Participants

3

Reactant 2

HCID 22628347(RS)-5-Benzyloxy-2-bromomethyl-2,3-dihydro-benzofuranHCID 22628418HCID 22628418, compound

Product 1

HCID 22628370HCID 22628370, compound

Procedure

The title compound MS: m/e=444.6 (M+H+) was prepared from 4-(2-methyl-benzyl)-piperidin-4-ol and 5-benzyloxy-2-(RS)-bromomethyl-2,3-dihydro-benzofuran.

Sources & evidence

ORD record
ord-2371840ac9f14fc280ab8e685642f0b6
Source dataset
uspto-grants-2002_03
Patent number
US06359138B1

Reaction notes

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