HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(4-Chlorophenyl)methyl]piperidin-4-ol → (s)-1-(5-Methoxy-2,3-dihydro-benzofuran-2-ylmethyl)-4-(4-chloro-benzyl)-piperidin-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(4-Chlorophenyl)methyl]piperidin-4-ol | HCID 22245493 | — |
| Reactant | (S)-Toluenesulfonic acid 5-methoxy-2,3-dihydro-benzofuran-2-ylmethyl ester | HCID 88124042 | — |
| Product | (s)-1-(5-Methoxy-2,3-dihydro-benzofuran-2-ylmethyl)-4-(4-chloro-benzyl)-piperidin-4-ol | HCID 54036117 | — |
Reaction Steps
The title compound, MS: m/e=387.9 (M+H+), was prepared from 4-(4-chloro-benzyl)-piperidin-4-ol and (S)-toluenesulfonic acid 5-methoxy-2,3-dihydro-benzofuran-2-ylmethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06359138B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-a6099842a67b479794cc629d526c93c5 |
| Source note | uspto-grants-2002_03 |