Triethylamine → HCID 22628388, compound

Participants

Reaction Steps

(RS)-2-bromomethyl-2,3-dihydro-benzofuran-5-ylamine (410 mg, 1.80 mmol), methansulfonyl-chloride (206 mg, 1.8 mmol), Et3N (182 mg, 1.80 mmol) were dissolved in CH2Cl2 (50 ml) and stirred overnight at room temperature. Solvent was then evaporated and the residue was chromatographed over SiO2 (Merck 230-400 mesh) eluting with CH2Cl2—MeOH (95:5) to provide (RS)-N-(2-bromomethyl-2,3-dihydro-benzofuran-5-yl)-methansulfonamide (516 mg, 94%) as an oil. MS: m/e=305.9 (M−H+)

Provenance & Evidence