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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278470Generated: November 1, 2026

(3S)-3-benzyloxy-1,2-epoxybutane → (2S)-2-benzyloxy-5-(1-naphthyl)pentan-3-ol

https://huagongshe.com/reaction/278470

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S)-3-benzyloxy-1,2-epoxybutaneHCID 57223577—
ReactantHCID 178478993HCID 178478993—
Product(2S)-2-benzyloxy-5-(1-naphthyl)pentan-3-olHCID 57192398—

Reaction Steps

(2S)-2-benzyloxy-5-(1-naphthyl)pentan-3-ol was prepared from (3S)-3-benzyloxy-1,2-epoxybutane (obtained in Preparation 9) and 1-naphthylmethylmagnesium chloride (J. Am. Chem. Soc. 1943, 65, 295).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06359145B1
Source datasetuspto-grants-2002_03
ORD IDord-33e6cca0da904967b72518ad71821d70
Source noteuspto-grants-2002_03