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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278475Generated: October 26, 2026

Benzene, 1-iodo-3-(trifluoromethyl)- → Methyl 4-[3-(trifluoromethyl)phenyl]-2-oxobutyrate

https://huagongshe.com/reaction/278475

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-iodo-3-(trifluoromethyl)-HCID 67868—
ReactantMethyl 2-hydroxybut-3-enoateHCID 545123—
ProductMethyl 4-[3-(trifluoromethyl)phenyl]-2-oxobutyrateHCID 18370956—

Reaction Steps

Methyl 4-[3-(trifluoromethyl)phenyl]-2-oxobutyrate was prepared as an oil from 3-iodobenzotrifluoride and methyl 2-hydroxy-3-butenoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06359145B1
Source datasetuspto-grants-2002_03
ORD IDord-68504ab90cab4888840d0bf90ae7086f
Source noteuspto-grants-2002_03