Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278476Generated: October 25, 2026

Methyl 2-hydroxybut-3-enoate → Methyl 4-[3-(tert-butyldimethylsilyloxy)phenyl]-2-oxo-butyrate

https://huagongshe.com/reaction/278476

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-hydroxybut-3-enoateHCID 545123—
Reactant3-(t-Butyldimethylsiloxy)iodobenzeneHCID 2757280—
ProductMethyl 4-[3-(tert-butyldimethylsilyloxy)phenyl]-2-oxo-butyrateHCID 22628472—

Reaction Steps

Methyl 4-[3-(tert-butyldimethylsilyloxy)phenyl]-2-oxo-butyrate was prepared as a yellow oil from 3-(tert-butyldimethylsilyloxy) iodobenzene and methyl 2-hydroxy-3-butenoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06359145B1
Source datasetuspto-grants-2002_03
ORD IDord-aa3f6ffcaef64adf90e8c219dafe00f6
Source noteuspto-grants-2002_03