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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278485Generated: October 31, 2026

Phenethyl bromide → (3S,4S)-4-(tert-butyldimethylsilyloxy)-1-phenylpentan-3-ol

https://huagongshe.com/reaction/278485

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenethyl bromideHCID 7666—
Reactant(2S)-2-[(tert-butyldimethylsilyl)oxy]propanalHCID 10954305—
Product(3S,4S)-4-(tert-butyldimethylsilyloxy)-1-phenylpentan-3-olHCID 57308546—

Reaction Steps

(2S,3S)-2-(tert-butyldimethylsilyloxy)-5-phenyl-pentan-3-ol was prepared from (S)-2-(tert-butyldimethylsilyloxy)propanal (Synthesis 1996, 652, 3.00 g) and 2-phenylethyl bromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06359145B1
Source datasetuspto-grants-2002_03
ORD IDord-c41a0839434d45489edad8878a8b2c81
Source noteuspto-grants-2002_03