Water → 4-Bromo-N,N-diisopropylbenzylamine

Participants

Role	Name	HCID	Charge
Reactant	Water	HCID 962	—
Reactant	Diisopropylamine	HCID 7912	—
Reactant	Potassium Carbonate	HCID 11430	—
Reactant	4-Bromobenzyl bromide	HCID 68527	—
Solvent	Dimethylformamide	HCID 6228	—
Product	4-Bromo-N,N-diisopropylbenzylamine	HCID 598770	—

Reaction Conditions

Temperature	80 °C

Reaction Steps

A mixture of 4-bromobenzylbromide (5.0 g), N,N-diisopropylamine (7.85 ml) and potassium carbonate (2.76 g) in dimethylformamide (50 ml) was stirred at 80° C. for 2 hours. To the mixture was added water, and the mixture was extracted with ether. The extract was washed with water, dried (MgSO4) and concentrated to give the title compound (5.0 g).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06359134B1
Source dataset	uspto-grants-2002_03
ORD ID	ord-0947629a38f245a280dfe00ef647a3cd
Source note	uspto-grants-2002_03