HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278575Generated: October 30, 2026
Hydrochloric Acid → HCID 22628122, compound
https://huagongshe.com/reaction/278575
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 22628040 | HCID 22628040 | — |
| Solvent | Tetrahydrofuran ethanol | HCID 21873804 | — |
| Product | HCID 22628122 | HCID 22628122 | 90.9% |
Reaction Steps
A mixture of ethyl 2-(2-tert-butoxycarbonylamino-5-pyridyl)-4-methyl-5-thiazolecarboxylate (180 mg), 1N NaOH (2 ml) and EtOH-THF (2:1, 6 ml) was stirred at 70° C. for 1 hour, to which was added 1 N HCl (2 ml) to give the title compound (151 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06359134B1 |
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| Source dataset | uspto-grants-2002_03 |
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| ORD ID | ord-4d1673e0bdf846b187f74d59926bbe3c |
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| Source note | uspto-grants-2002_03 |
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