HCID 22628150, compound → HCID 22628063, compound

Participants

Reaction Steps

To a solution of 1-(4-diisopropylaminomethylbenzoyl)-4-[6-(2,2, 2-trichloroethoxycarbonylamino)naphthalene-2-sulfonyl]piperazine (125 mg) in acetic acid (3 ml) was added zinc dust (1.0 g), and the solution was stirred at room temperature for 3 hours. Insoluble materials were filtered off, and the filtrate was concentrated. The residue was dissolved in 1 N hydrochloric acid and the solution was made alkaline with 1 N sodium hydroxide solution. The precipitate was filtered, washed with water and dried to give pale purple solid of the title compound (92 mg).

Provenance & Evidence