Diethyl Ether → HCID 15385696, compound

Participants

Reaction Steps

A solution of Nα-17-tetrabenzo(a,c,g,i)fluorenylmethoxycarbonyl-L-phenylalanine tert-butyl ester (68.2 mg, 0.106 mmol) in trifluoroacetic acid (950 μl) and water (50 μl) was sonicated for 2.5 h. The solvent was removed in vacuo to give a purple residue. A mixture of diethyl ether and petrol b.p. 40-60° C. (1:1) was added. The precipitate obtained was chilled overnight, filtered, washed with petrol and finally dried in a vacuum desiccator over P2O5 to give compound (55) (57.6 mg, 93);

Provenance & Evidence