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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278829Generated: October 26, 2026

Hydrochloric Acid → Resveratrol

https://huagongshe.com/reaction/278829

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPolydatinHCID 5281718—
SolventWaterHCID 962—
ProductResveratrolHCID 44515497,491.898%

Reaction Conditions

Temperature100 °C

Reaction Steps

The following example illustrates conversion of a β-D-glycosylated stilbene to the aglycone. 200 mg of 90% trans-piceid (3,4′5-trans-trihydroxystilbene -3-β-mono-D-glucoside, BZ1-69-1) was mixed with 5 ml of concentrated hydrochloric acid and 95 ml water (5% HCl v/v) and refluxed with agitation at 100° C. for 90 minutes to yield 114 g (57% yield) trans-resveratrol (trans-3,4′,5-trihydroxystilbene).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06361815B1
Source datasetuspto-grants-2002_03
ORD IDord-ceee14f390a041b695a415d57ac7161c
Source noteuspto-grants-2002_03