HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butanenitrile, 3-imino- → 1-(6-chloropyridazin-3-yl)-3-methyl-1H-pyrazol-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butanenitrile, 3-imino- | HCID 70698 | — |
| Reactant | 3-Chloro-6-hydrazinopyridazine | HCID 100787 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(6-chloropyridazin-3-yl)-3-methyl-1H-pyrazol-5-amine | HCID 6408845 | — |
Reaction Steps
A mixture of 14.5 g (0.1 moles) of 3-chloro-6-pyridazinyl-hydrazine, 8.5 g (0.1 moles) of 3-iminobutyronitrile and 150 ml of ethanol is heated to reflux for 9 hours. After cooling the separated crystals are filtered, washed with ethanol and dried. Yield: 15.6 g (74.0%); m.p.: 148°-150° C. The hydrochloride melts at 157°-159° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04224325 |
| Source dataset | uspto-grants-1980_09 |
| ORD ID | ord-f95930bf92b241b29b08fdf04c19328f |
| Source note | uspto-grants-1980_09 |