Formaldehyde → HCID 22623921, compound

HRID 278962Notes

Reaction equation

HRID 278962 reaction equation
C=O.S(=O)(=O)(O)O.[CH:8]1[CH:17]=[C:16]2[C:18]([O:20][C:21](=[O:22])[C:14]3=[C:15]2[C:10](=[CH:11][C:12]([OH:23])=[CH:13]3)[CH:9]=1)=[O:19].[O:24]1[CH2:29]COC[CH2:25]1>>[CH:9]1[C:10]2[C:15]3[C:16]([C:18](=[O:19])[O:20][C:21](=[O:22])[C:14]=3[CH:13]=[C:12]3[C:11]=2[CH2:29][O:24][CH2:25][O:23]3)=[CH:17][CH:8]=1

Participants

5

Reactant 4

HCID 712FormaldehydeHCID 1118Sulfuric AcidHCID 312751,4-DioxaneHCID 5985393-Hydroxy-1,8-naphthalic anhydride

Product 1

HCID 22623921HCID 22623921, compound

Conditions

Temperature
80 °C

Procedure

Paraformaldehyde (16.0 g, 530.0 mmol) and concentrated sulfuric acid (80 mL) were added to a suspension of 3-hydroxy-1,8-naphthalic anhydride (10.24 g, 48.0 mmol) in dioxane (500 mL). The mixture was heated to 80° C. for 2 hours under stirring. After cooling, the reaction mixture was poured into ice water (1000 mL). The precipitate was filtered and dried to give 12.0 g of the title compound.

Workup

  1. temperatureAfter cooling
  2. filtrationThe precipitate was filtered
  3. customdried

Sources & evidence

ORD record
ord-487835f78cf64ea191361a3e1398b61a
Source dataset
uspto-grants-2002_03
Patent number
US06362181B1

Reaction notes

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