Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | HCID 22623962 | HCID 22623962 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 22623933 | HCID 22623933 | 94.8% |
Reaction Steps
Pyrrolidine (0.85 g, 12.0 mmol) was added to 5-acetamido-2-tert-butyloxy-6-chloro benzo[de]isoquinoline-1,3-dione (0.30 g, 0.8 mmol, from Example P2). The solution was heated at 100° C. overnight followed by addition of water (10 mL). The precipitate was filtered to give 0.30 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06362181B1 |
|---|
| Source dataset | uspto-grants-2002_03 |
|---|
| ORD ID | ord-a98f9d71204c405f937c28c7e86a546d |
|---|
| Source note | uspto-grants-2002_03 |
|---|
