Acetic Anhydride → HCID 22623959, compound

HRID 278982Notes

Reaction equation

HRID 278982 reaction equation
[NH2:1][C:2]1[CH:12]=[C:11]([Cl:13])[C:10]2[C:14]3[C:3]=1[CH2:4][CH2:5][C:6]=3[CH:7]=[CH:8][C:9]=2[Cl:15].[C:16](OC(=O)C)(=[O:18])[CH3:17]>C(O)(=O)C>[C:16]([NH:1][C:2]1[CH:12]=[C:11]([Cl:13])[C:10]2[C:14]3[C:3]=1[CH2:4][CH2:5][C:6]=3[CH:7]=[CH:8][C:9]=2[Cl:15])(=[O:18])[CH3:17]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 22623947HCID 22623947, compound

Product 1

HCID 22623959HCID 22623959, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
10 °C

Procedure

A suspension of 3-amino-5,6-dichloroacenaphthene (3.3 g, 13.8 mmol, from Example D4) in 10 mL of acetic acid was treated with 10 mL of acetic anhydride and heated on a steam bath for 1 hour. The reaction was cooled to 10° C., and the solid was removed by filtration, washed with petroleum ether, and dried in vacuo to give 3.5 g of the title compound.

Workup

  1. temperatureheated on a steam bath for 1 hour
  2. customthe solid was removed by filtration
  3. washwashed with petroleum ether
  4. customdried in vacuo

Sources & evidence

ORD record
ord-134e5ac3d539421db57900a6dfb154eb
Source dataset
uspto-grants-2002_03
Patent number
US06362181B1

Reaction notes

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