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1H,3H-Naphtho[1,8-cd]pyran-1,3-dione, 6-chloro- → 6-chloro-2-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1H,3H-Naphtho[1,8-cd]pyran-1,3-dione, 6-chloro- | HCID 77672 | — |
| 反応物 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 6-chloro-2-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione | HCID 3236373 | 80.8% |
反応手順
4-Chloro-1,8-naphthalic anhydride (1.4 g, 6.0 mmol) and hydroxylamine hydrochloride (0.8 g, 11.5 mmol) were reacted in pyridine (50 mL) following the procedure of Example 1 to give 1.2 g of the title compound, mp 234-236° C.;
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06362181B1 |
| 出典データセット | uspto-grants-2002_03 |
| ORD ID | ord-824689ddb95649a8b1c366ea671fd961 |
| 出典メモ | uspto-grants-2002_03 |