HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminonaphthalene-1,8-dicarboxylic anhydride → 6-Amino-2-hydroxy-benzo[de]isoquinoline-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminonaphthalene-1,8-dicarboxylic anhydride | HCID 80990 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 6-Amino-2-hydroxy-benzo[de]isoquinoline-1,3-dione | HCID 15896245 | 97.4% |
Reaction Steps
4-Amino-1,8-naphthalic anhydride (0.2 g, 0.9 mmol) and hydroxylamine hydrochloride (0.1 g, 1.4 mmol) were reacted in pyridine (20 mL) following the procedure of Example 1 to give 0.2 g of the title compound, mp >360° C.;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06362181B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-5c6e1141e8ca4934b1d04089a796f586 |
| Source note | uspto-grants-2002_03 |