5-Amino-2-tert-butyldimethylsilyoxy-benzo[de]isoquinoline-1,3-dione → 5-Amino-2-hydroxy-benzo[de]isoquinoline-1,3-dione

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Reaction Steps

A solution of compound 5-amino-2-tert-butyldimethylsilyoxy-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline (0.8 g, 2.3 mmol, from Example B) in 2% HCl in ethanol (50 mL) was stirred at room temperature for 1 hour. The solid which formed was filtered and dried, to give 0.4 g of the title compound, mp 288-294° C. (dec).

Provenance & Evidence