Water → HCID 57187157, compound

Participants

Reaction Steps

A solution of Oxone (0.356 g. 0.579 mM) in water (2.5 ml) was added to a stirred suspension of the title product from Example 37 (0.117 g. 0.276 mM) in EtOH (10 ml) and the mixture heated at gentle reflux for 2.75 hours. The mixture was allowed to cool. The solid which precipitated was filtered, washed with water and ether to give the title compound (0.1 09 g). MS: 457 (MH+); NMR(250 MHz) 1.83 (3H, s); 3.38 (3H, s); 3.45 (2H, t); 3.85 (1H, m); 4.23 (1H, t); 4.79 (1H, m); 7.78 (2H, d); 8.0 (2H, d); 8.08 (2H, m); 8.24 (1H, t); 8.48 (1H, s); 10.01 (1H, s).

Provenance & Evidence