HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)aniline → 3-oxo-N-[3-(trifluoromethyl)phenyl]butanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)aniline | HCID 7375 | — |
| Reactant | Diketene | HCID 12661 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 3-oxo-N-[3-(trifluoromethyl)phenyl]butanamide | HCID 744366 | — |
Reaction Steps
m-Trifluoromethyl aniline (32.22 g) in benzene was dissolved in benzene and diketene added slowly with mixing. The reaction mixture was allowed to stand at 25° C. The resulting solid product was recrystallized from ethanol to yield 3'-trifluoromethyl acetoacetanilide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04224334 |
| Source dataset | uspto-grants-1980_09 |
| ORD ID | ord-e2e79f9094af4c188695b3e1de86223b |
| Source note | uspto-grants-1980_09 |