3-(3,5-Bis(trifluoromethyl)phenylamino)-2-(4-chlorophenylsulfonyl)-3-methylsulfanyl-2-propenenitrile → HCID 73986583, compound

Participants

Reaction Steps

3-(3,5-Bis(trifluoromethyl)phenylamino)-2-(4-chlorophenyisulfonyl)-3-methylsulfanyl-2-propenenitrile (0.400 g, 0.8 mmol) was stirred in n-propylamine (1.0 ml) at 75° C. in a sealed flask for 19 h. Work up as described in Example 1, 2) gave 266 mg (65%) of the title compound as white crystals. Mp 196.5-198.5° C. 1H NMR (300 MHz, CDCl3): δ=0.9 (t, 3H), 1.55 (p, 2H), 2.88 (q, 2H), 7.40 (s, 2H), 7.48 (d, 2H), 7.68 (s, 1H), 7.81 (d, 2H); MA calc for C20H16ClF6N3O2S: C, 46.93%; H, 3.15%; N, 8.21%. Found: C, 46.82%; H, 3.19%; N, 8.10%.

Provenance & Evidence