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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 279191Generated: October 29, 2026

1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)- → HCID 3002957, compound

https://huagongshe.com/reaction/279191

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)-HCID 10131191—
ReactantHCID 10848747HCID 10848747—
ProductHCID 3002957HCID 3002957—

Reaction Steps

(2R,3S)-2-(2,4-Difluorophenyl)-3-methyl-2-(1H-1,2,4-triazol-1-yl)methyloxirane was reacted with 1-[4-(2-methyl-4-thiazolyl)phenyl]-2(1H,3H)-imidazolone in the same manner as in Working Example 11 to give 1-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(2-methyl-4-thiazolyl)phenyl]-2(1H,3H)-imidazolone (Compound 30).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06362206B1
Source datasetuspto-grants-2002_03
ORD IDord-67a0b376abe14498976b88e43e845f90
Source noteuspto-grants-2002_03