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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 279241Generated: October 30, 2026

4-Toluenesulfonyl chloride → HCID 22662906, compound

https://huagongshe.com/reaction/279241

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Toluenesulfonyl chlorideHCID 7397—
Reactant(Isoquinolin-4-yl)methanolHCID 12746377—
SolventPyridineHCID 1049—
ProductHCID 22662906HCID 22662906—

Reaction Conditions

Temperature0 °C

Reaction Steps

The title compound from Step A above is dissolved in anhydrous pyridine and cooled to 0° C. with stirring, 4-Toluenesulfonyl chloride is added and the reaction is carried out as described in Preparative Example 60, Step D to give the title compound which may be used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06362188B1
Source datasetuspto-grants-2002_03
ORD IDord-25b5ed9a642c45d8aa2d0a5f1581efed
Source noteuspto-grants-2002_03