Dimethyl Sulfoxide → 2-{[(Ethenyloxy)carbonyl]oxy}ethyl 2-methylprop-2-enoate

HRID 279439Notes

Reaction equation

HRID 279439 reaction equation
[C:1](=[O:15])([O:12][CH:13]=[CH2:14])[O:2][C:3]1[CH:8]=CC([N+]([O-])=O)=CC=1.OCC[O:19][C:20](=[O:24])[C:21]([CH3:23])=[CH2:22].CS(C)=O.[OH-].[Na+]>O>[C:1](=[O:15])([O:12][CH:13]=[CH2:14])[O:2][CH2:3][CH2:8][O:24][C:20](=[O:19])[C:21]([CH3:23])=[CH2:22]

Participants

6

Reactant 4

HCID 679Dimethyl SulfoxideHCID 133602-Hydroxyethyl MethacrylateHCID 14798Sodium HydroxideHCID 11183405p-nitrophenyl vinyl carbonate

Product 1

HCID 231870742-{[(Ethenyloxy)carbonyl]oxy}ethyl 2-methylprop-2-enoate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of p-nitrophenyl vinyl carbonate, hydroxyethylmethacrylate, DMSO and sodium hydroxide is stirred at room temperature for a minimum of 12 hours. Reaction completion is monitored by G.C. The solution is drowned into water and the mixture extracted with ethyl acetate. The product solution is washed with water, dried with magnesium sulfate, then stripped to an oil under vacuum. The crude product is then purified.

Workup

  1. customReaction completion
  2. extractionthe mixture extracted with ethyl acetate
  3. washThe product solution is washed with water
  4. dry with materialdried with magnesium sulfate
  5. customThe crude product is then purified

Sources & evidence

ORD record
ord-85135ddd2ee94013b167317a3cada355
Source dataset
uspto-grants-2002_03
Patent number
US06362363B1

Reaction notes

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