Piperidine → 9-gamma-Piperidinopropyl-9,10-dihydro-9,10-methanoanthracene

Participants

Role	Name	HCID	Charge
Reactant	Piperidine	HCID 8082	—
Reactant	9-gamma-Chloropropyl-9,10-dihydro-9,10-methanoanthracene	HCID 20519962	—
Solvent	Ethyl Acetate	HCID 8857	—
Product	9-gamma-Piperidinopropyl-9,10-dihydro-9,10-methanoanthracene	HCID 13069077	—

Reaction Conditions

Temperature	100 °C

Reaction Steps

A mixture of 9-γ-chloropropyl-9,10-dihydro-9,10-methanoanthracene (50 mg) and piperidine (0.1 ml) was heated at 100° C. for 3 hours. The reaction mixture was diluted with ethyl acetate, washed with water, dried over anhydrous sodium sulfate and evaporated to dryness to give 9-γ-piperidinopropyl-9,10-dihydro-9,10-methanoanthracene, which was converted into its hydrochloride. M.P. 280°-283° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04224344
Source dataset	uspto-grants-1980_09
ORD ID	ord-00217097ac874e0dbafe0515d61266bf
Source note	uspto-grants-1980_09